Rosaliss™ helps restore homeostasis and prevents the senescence associated decrease of MARCKSL1 expression
Cells: Normal Human Keratinocytes with senescent model
Product application: Rosaliss™ at 0.1 % (1x/d) for 6h after senescence induction
Evaluation: qPCR of MARCKSL1
The qPCR values are presented as a percentage of the control and corresponded to relative quantification calculated from three replicates. Error bars corresponded to the calculated RQmin and RQmax values based on standard deviation of the mean expression level.
*** Highly significant with Student’s t test compared to non senescent keratinocytes in white or to senescent keratinocytes in grey
Rosaliss™ helps provide skin capital to self-repair over 72 hours
Rosaliss™ aids in skin texture smoothness (fine lines)
volunteer 11; age 60 years old
Healthy microbiome
Rosaliss™ helps skin maintain claudin-1 expression in a dysbiosis state which is a key protein of tight junctions linked to an optimized skin repair

Model: RHE infected by S. epidermidis : S. aureus ratio
Product application: Rosaliss at 1%
Evaluation: quantification of Claudin-1 immunostaining
Claudin-1 is a key protein of tight junctions at the upper layer of epidermis. Recent research shows link between Claudin-1 and optimized skin repair.