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Orsirtine™ ISR

Orsirtine™ ISR is a breakthrough anti-aging technology, based on sirtuins, that promotes skin longevity ex vivo.




Product Overview

INCI Aqua (and) Glycerin (and) Oryza Sativa (Rice) Extract

Orsirtine™ ISR is positioned for anti-aging facial products. This product promotes long-term skin benefits and protection from environmental aggression. It is extracted from rice (oryza sativa) and contains sirtuin (SIRT1)-activating compounds, also called 'STACS'.

Product Specifications

Form: Limpid solution
Odor: Characteristic
Color: Pale yellow to yellow
pH: 4.0 - 5.0
Preservative system: Potassium sorbate
Use level: 1.0% (clinically tested at 3%)

Features & Benefits

COSMOS validated
In vitro lab tests demonstrate a decrease in
cell senescence
In vitro lab tests demonstrate extended longevity of aged keratinocytes and fibroblasts
In vitro studies show SIRT1 content increased in the skin more than polyphenols
Skin protection and repair were demonstrated in vitro after UV and oxidative damage
Ex vivo studies demonstrate an improvement in the appearance of skin exposed or not exposed to UV


Ideal for anti-aging skin care products to help increase skin protection in order to decrease premature aging.  Also for daily care products to help protect the skin from daily environmental

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