Avoid Data Center Downtime: How Krytox® GPL 206 Stops Leaks

In modern data centers—especially those running GPU-intensive AI and machine learning workloads—liquid cooling is no longer optional. It is a necessity. But the hidden weak point in many closed-loop systems is not the fluid, the pump, or the manifold. It is the O-ring. If you are not using the right lubricant, a simple seal failure could knock your servers offline. 

 

The Risk: One O-Ring, One Leak, Total System Failure 


A data center engineer recently called us with a high-stakes problem. 

Their liquid-cooled loop was leaking at a quick disconnect fitting. The culprit? An incompatible lubricant had degraded the O-ring. Without the proper seal, pressure dropped and coolant levels began to fall—threatening a rack of GPUs designed to run 24/7, worth over $100,000. 

A missed alarm or delayed response could have meant overheating, shutdown, or irreversible hardware damage. In AI workloads, even 60 seconds of downtime is expensive. 
 

The Fix: Krytox® GPL 206 for O-Ring Reliability in Liquid Cooling Systems 


The engineer swapped in a compatible O-ring and applied Krytox® GPL 206, a PFPE-based grease trusted in aerospace, semiconductor, and now, advanced liquid cooling environments. Problem solved. Leak stopped. System saved. 
 

Why Krytox® GPL 206 Works Where Others Fail 

  • Chemically inert PFPE base oil: Won’t degrade rubber, silicone, or fluoropolymer O-rings 
  • Thermal stability up to 260°C: Withstands GPU cooling loop temps with ease 
  • Nonreactive with DOWFROST™, glycol, and water: Perfect for hybrid coolant systems 
  • Long-term lubrication: Prevents microcracking, hardening, and shrinkage in seals 
  • Supports clean assembly and maintenance: No migration, gumming, or staining 

What Is at Stake: Cooling System Leaks = Uptime Risk 


Liquid cooling is only as reliable as the seals holding it together. Without the right lubricant, quick connects become slow leaks—and a minor O-ring failure can escalate into: 
  • Unplanned downtime 
  • Thermal shutdowns 
  • GPU and motherboard damage 
  • High-cost emergency service calls 

Application Spotlight: Quick Connects, Coolant Fills, & Seals 


Whether you are assembling a new rack or refilling a closed loop, Krytox® GPL 206 ensures your O-rings perform under pressure. Typical applications include: 
 
  • GPU and CPU loop quick disconnect O-rings 
  • Fill port seals and service valves 
  • Pressure-tested lines using DOWFROST™ LC, water, or other glycol-based coolants 
 

Is Your System at Risk? 

 
  • Are you using hydrocarbon or silicone greases near your O-rings? 
  • Have you seen small coolant losses after maintenance cycles? 
  • Are your O-rings discoloring, hardening, or flattening prematurely? 

If yes, Krytox® GPL 206 could be your simplest upgrade—and your biggest safeguard. 

Protect your servers before the next leak. 

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