Pharmaceutical Grade Preservatives and Sweeteners
Excipients play a major role in the success of a pharmaceutical formulation. They support and provide additional benefits for the effectiveness of the final product. Celanese provides preservatives to protect product quality and sweeteners to improve product flavor.
SUNETT® ACE-K (ACESULFAME POTASSIUM)
Sunett® Ace-K offers calorie-free sweetness to help mask bitter-tasting active ingredients in pharmaceutical products. Not only does it contribute to flavor, but it provides a variety of formulation benefits including stability, solubility, and ease of use.
- Zero calorie and not metabolized
- High-intensity sweetness at low concentrations
- Can be used in any thermal process up to 230°C
- Stable between pH 3 and 9
- 5-year shelf-life from date of manufacture
- Highly soluble and dissolves quickly
- High purity; free from insoluble and soluble impurities
- Available in multiple particle sizes for ease of incorporation
Sunett® Ace-K pharma grade complies with USP-NF, Ph. Eur., JPE requirements, and laws and regulations for excipients in the USA (FDA 21CFR 172.800). Celanese holds a DMF No/CEP No. 87 33/Type IV in the USA.
SUNETT® ACE-K APPLICATIONS
MEDICATED CHEWING GUM
Sunett® Ace-K provides high solubility to medicated chewing gum for an initial burst of sweetness by incorporating it into the shell of a coated pellet gum or in the powder coating of stick gum. For a slower release of sweetness, it can be encapsulated to deliver longer chew duration. It has great synergy with other sweeteners like aspartame and sucralose and can even be paired with sugar to boost the sweetness as needed.
GRANULES, POWDERS, AND EFFERVESCENT TABLETS
Sunett® Ace-K is an ideal sweetener for oral granules and powders due to its excellent stability, fast dissolution, and quick onset of sweetness when reconstituted. It can be added to the effervescent tablets to provide a more pleasant taste not just by adding sweetness but also masking the taste of active ingredients.
ORAL SOLUTIONS, SUSPENSIONS, AND SYRUPS
Sunett® Ace-K has excellent sweetness synergy to replace sweetness that’s lost when reducing or replacing sugar in liquid pharmaceutical products. Its stability makes it a great sweetener choice that won’t negatively interact with other ingredients in the formulation. It will dissolve quickly and completely without breaking down.
SUNETT® ACE-K GRADE BY APPLICATION
|Sunett® Ace-K Pharma Grade A|
|Sunett® Ace-K Pharma Grade C|
|Sunett® Ace-K Pharma Grade D|
Medicated chewing gum
Whether your applications is water- or oil-based, Nutrinova® Sorbates are preservatives that can improve shelf life by preventing microbial growth from yeast, mold, and bacteria. These high-quality sorbates are manufactured in a single-purpose plant in Germany resulting in reliable and consistent product.
- Outstanding protection against microbial growth
- Excellent storage stability in dry form
- Easy to dissolve or disperse
- Available in powder or granular forms
- Neutral taste and odor
- Favorable partition coefficient over other organic acids
Nutrinova® Sorbates pharma grades comply with USP-NF, Ph. Eur., and other national Pharmacopoeias.
NUTRINOVA® SORBATES GRADE BY APPLICATION
|Nutrinova® Sorbic Acid||Low-moisture or oil-based applications|