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SYLOID® 244
SYLOID® 244 is a synthetic amorphous silica recommended for use as a multifunctional excipient and anti-caking agent for food and industrial applications. Its highly porous structure ensures efficient oil absorption, absorbing up to two and a half times its weight.
- Manufacturer: Grace
- Product Line: SYLOID® Silicas
- Product: SYLOID® Silica Excipients
- Industries: Food & Beverage | Pharmaceuticals
- Authorized Countries: Canada | United States
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Overview
SYLOID® 244 is a multifunctional silica material from GRACE formulated to enhance product effectiveness, dissolution, stability, manufacturing efficiency, and more in pharmaceutical, nutraceutical, and industrial applications. It contains a unique chemically prepared amorphous silicon dioxide free-flowing powder with excellent properties, such as anti-caking, moisture protection, and electrostatic reduction. With a highly defined internal porosity that can be modified, SYLOID® 244 provides extraordinary adsorption, particle size distribution, porosity, density, and internal surface area to improve functionality and efficacy, in addition to minimizing the number of excipients needed. SYLOID® 244 has a strong affinity for moisture and organic-based liquid, providing enhanced absorbing properties, allowing the absorption of up to two and a half times its weight in liquid.
Specifications
Appearance: Powder
Color: White
Loss on ignition (1832°F): 8.5% max.
Loss on drying (105°C): 7.0% max.
SiO₂ content (dry basis): 99.6% min
pH (5% aqueous suspension): 6.0─8.3
Average particle size malvern® Mastersizer® 2000: 8.3 µm max.
Oil adsorption: 240 g/100g
Compacted bulk density: 0.10 g/cc
Pore volume (N₂): 1.4 g/ml
CAS no. 7631-86-9
Primary Chemistry: Amorphous silicon dioxide
Features & Benefits
Amorphous silicon dioxide
Multifunctional excipient
Free-flow additive
High purity
Improve manufacturing efficiency, dissolution, therapeutic effectiveness, and stability
Moisture protection
Reduces electrostatic charging
Improves flow properties
Moisture-assisted dry granulation
Oil absorption properties in lipid-based technologies
Prevents valve blockage in direct compression
Highly defined pore structures
Excellent porosity and particle size distribution
Enhanced moisture protection
Anti-sticking and anti-tacking
Absorbs up to 2 and a half times its weight in liquid
Matting agent
Anti-caking
Prevents clumping
Viscosity control
Problems Solved
Valve blockage in direct compression applications
Applications
APIs
Nutraceutical extracts
Film coatings
Sublingual and effervescent tablets
Related Categories
Food & Beverage
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