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SYLOID® 244
SYLOID® 244 is a synthetic amorphous silica recommended for use as a multifunctional excipient and anti-caking agent for food and industrial applications. Its highly porous structure ensures efficient oil absorption, absorbing up to two and a half times its weight.
SYLOID® 244 is a multifunctional silica material from GRACE formulated to enhance product effectiveness, dissolution, stability, manufacturing efficiency, and more in pharmaceutical, nutraceutical, and industrial applications. It contains a unique chemically prepared amorphous silicon dioxide free-flowing powder with excellent properties, such as anti-caking, moisture protection, and electrostatic reduction. With a highly defined internal porosity that can be modified, SYLOID® 244 provides extraordinary adsorption, particle size distribution, porosity, density, and internal surface area to improve functionality and efficacy, in addition to minimizing the number of excipients needed. SYLOID® 244 has a strong affinity for moisture and organic-based liquid, providing enhanced absorbing properties, allowing the absorption of up to two and a half times its weight in liquid.
Specifications
Appearance: Powder Color: White Loss on ignition (1832°F): 8.5% max. Loss on drying (105°C): 7.0% max. SiO₂ content (dry basis): 99.6% min pH (5% aqueous suspension): 6.0─8.3 Average particle size malvern® Mastersizer® 2000: 8.3 µm max. Oil adsorption: 240 g/100g Compacted bulk density: 0.10 g/cc Pore volume (N₂): 1.4 g/ml CAS no. 7631-86-9
Primary Chemistry: Amorphous silicon dioxide
Features & Benefits
Amorphous silicon dioxide Multifunctional excipient Free-flow additive High purity Improve manufacturing efficiency, dissolution, therapeutic effectiveness, and stability Moisture protection Reduces electrostatic charging Improves flow properties Moisture-assisted dry granulation Oil absorption properties in lipid-based technologies Prevents valve blockage in direct compression Highly defined pore structures Excellent porosity and particle size distribution Enhanced moisture protection Anti-sticking and anti-tacking Absorbs up to 2 and a half times its weight in liquid Matting agent Anti-caking Prevents clumping Viscosity control
Problems Solved
Valve blockage in direct compression applications
Applications
APIs Nutraceutical extracts Film coatings Sublingual and effervescent tablets
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Thank you
Thank you for your inquiry and interest in ChemPoint. We will respond to you shortly.
ChemPoint will not under any circumstances release personal user information to individuals or companies. All information collection is solely used to support ChemPoint customers service communications. Read our Privacy Notice.
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