SYLOID® 72 FP

SYLOID® 72 FP is an advanced mesoporous silicon dioxide (CAS no. 7631-86-9) formulated by GRACE to provide a moderate pore volume, large internal surface area, and bulk density of 0.16 g/cc. It acts as a high-performance excipient with multiple application possibilities in the pharmaceutical and nutraceutical industries.

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Specifications

Appearance: Powder
Color: White
Loss on ignition (1832°F): 8.5% max.
Loss on drying (150°C): 4.0% max.
SiO₂ content (dry basis): 99.0% min
Sulfate (SO₄): 0.5% max
pH (5% slurry): 6.0─8.0
Average particle size malvern® Mastersizer®: 4.6─6.7 µm max.
Wet Screen through 325 Mesh (U.S. Standard): 99.95% min.
Apparent Bulk Density: 0.11 g/cc
Compacted Bulk Density: 0.16 g/cc
Chlorides (Cl): 0.1 wt. % max.
Mercury (Hg): ≤0.1 ppm
Iron Oxide (Fe₂O₃): ≤200 ppm max.
Aluminum oxide (Al₂O₃): ≤0.2 wt. % max.
Sodium oxide (Na₂O) ≤0.2 wt. %
Calcium Oxide (CaO): ≤0.14 wt. % max.
Arsenic (As): ≤0.5 ppm
Lead (Pb): ≤0.5 ppm
Sodium sulfate (Na₂SO₄): ≤1.5 wt. %
Heavy metals: ≤20 ppm
Total aerobic plate count: ≤500 cfu/g
CAS no. 7631-86-9
Primary Chemistry: Amorphous silicon dioxide

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Manufacturer
Grace
Product Line
SYLOID® Silicas
Product
SYLOID® Silica Excipients
Industries
Food & Beverage Pharmaceuticals
Authorized Countries
Canada United States
supplier logo

Specifications

Appearance: Powder
Color: White
Loss on ignition (1832°F): 8.5% max.
Loss on drying (150°C): 4.0% max.
SiO₂ content (dry basis): 99.0% min
Sulfate (SO₄): 0.5% max
pH (5% slurry): 6.0─8.0
Average particle size malvern® Mastersizer®: 4.6─6.7 µm max.
Wet Screen through 325 Mesh (U.S. Standard): 99.95% min.
Apparent Bulk Density: 0.11 g/cc
Compacted Bulk Density: 0.16 g/cc
Chlorides (Cl): 0.1 wt. % max.
Mercury (Hg): ≤0.1 ppm
Iron Oxide (Fe₂O₃): ≤200 ppm max.
Aluminum oxide (Al₂O₃): ≤0.2 wt. % max.
Sodium oxide (Na₂O) ≤0.2 wt. %
Calcium Oxide (CaO): ≤0.14 wt. % max.
Arsenic (As): ≤0.5 ppm
Lead (Pb): ≤0.5 ppm
Sodium sulfate (Na₂SO₄): ≤1.5 wt. %
Heavy metals: ≤20 ppm
Total aerobic plate count: ≤500 cfu/g
CAS no. 7631-86-9
Primary Chemistry: Amorphous silicon dioxide

Features & Benefits

  • Amorphous silicon dioxide
  • Multifunctional excipient
  • Free-flow additive
  • High purity
  • Improve manufacturing efficiency, dissolution, therapeutic effectiveness, and stability
  • Moisture protection
  • Reduces electrostatic charging
  • Improves flow properties
  • Moisture-assisted dry granulation
  • Excellent compatibility with actives
  • Oil absorption properties in lipid-based technologies
  • Prevents valve blockage in direct compression
  • Highly defined pore structures
  • Excellent porosity and particle size distribution
  • Enhanced moisture protection
  • Anti-sticking and anti-tacking
  • Absorbs up to 1.5 ml of liquid per gram
  • Matting agent
  • Anti-caking
  • Prevents clumping
  • Viscosity control

Problems Solved

Valve blockage in direct compression applications

Applications

APIs
Pharmaceutical products
Nutraceutical extracts
Film coatings
Sublingual and effervescent tablets

Related Applications
Pharmaceuticals
Related Categories
Food & Beverage
Related Functions
Food & Beverage Pharmaceuticals

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