Glycolic Acid Disinfectants


    The demand for disinfectants and sanitizers continues to rise while some active chemicals are receiving scrutiny for potential health and environmental concerns. Are you looking for a new active ingredient to add to your portfolio?

     

    Look no further; Glyclean™ D was developed to meet the current and future market needs for hard surface disinfection.


What is Glyclean™ D70?

 

Glyclean™ D70 is a glycolic-acid-based EPA registered disinfectant from The Chemours Company that offers broad-spectrum disinfectant claims. It is registered as a manufacturing-use-only product and available for use through sub-registration. Glyclean™ D70 has four registered formulations in the United States and one in Europe for hard-surface cleaning and sanitization.

 

Watch this video to learn about Glyclean™ D70, The Future of Hard Surface Disinfection.

 


Why is Glyclean™ the Future of Surface Disinfection?

 

  • Naturally occurring, readily biodegradable
  • Excellent performing disinfectant with a positive chemical profile
  • Cleans and disinfects in one step
  • Safe for use in designated disinfection applications
  • Available for use in EPA-registered formulations designed to meet future regulations
  • Low VOC, safer for people and the environment
  • Attacks microorganism cell walls/membranes and disrupts essential cellular functions
  • Dual mode of action minimizes the chance of organisms developing resistance
  • No need to pre-clean surfaces prior to disinfection
  • An acid cleaning solution that sequesters and solubilizes multivalent metals

Glyclean™ D70 Disinfection and Antimicrobial Activity

 

Mode of Action: Glyclean™ D70 utilizes its small molecular size and dual functional groups (COOH and OH) to provide a multi-mode of action for microbial cell disruption. As a result of this duality of action, the development of microbial resistance is dramatically minimized with the use of Glyclean™ disinfectants.

 

Bactericidal Activity: Glyclean™ D70 kills a very wide range of both Gram-positive and Gram-negative bacteria. Glyclean™ D70 has demonstrated efficacy against E.coli (including O157:H7), Listeria welshimeri, Pseudomonas, Salmonella, and Staphylococcus. Full EN 13697 studies are available for review.

 

Viricidal Activity: Glyclean™ D70 is an effective viricidal agent as well. Various studies have demonstrated that Glyclean™ D70 effectively kills both large and small viruses and both enveloped and non-enveloped viruses. Testing has shown efficacy against SARS-CoV-2 (COVID-19), Influenza type A, Rhinovirus type 37, and Herpes type 1.


Glyclean™ Bactericidal, Viricidal, and Fungicidal Efficacy

 

Chemours Glyclean™ D70 has been registered with the US EPA as an active ingredient in the formulation of disinfectants on hard, nonporous surfaces for household, industrial, institutional, or commercial use. A range of Glyclean™ D clean-and-disinfect formulated products for hard surfaces have also been registered with the US EPA and are available for sub-registration purposes.

 

 

Glyclean™ D70 may also be used in formulating disinfecting cleaners for use in agricultural premises and food processing facilities, as well as on food processing equipment. Label directions on the end-use product must specify that all food, feed, and animals be removed before application and that a potable water rinse must follow the application.

 

In the EU, the Chemours Company is fully committed to completing the BPR process, and Glyclean™ D is used in formulations for National Registrations. The BPR process provides a transition period that supports registering new formulations with Glyclean™ D.

 

Glyclean™ D showed excellent efficacy against a broad range of bacteria and viruses, including SARS-CoV-2, the cause of COVID-19, at a (> 99.9) kill rate in one minute. Details describing the bactericidal, viricidal, and fungicidal efficacy of Glyclean™ are shown in the tables below. The results reported herein were performed by third-party contract laboratories:

 

Glyclean™ North American Studies

 

Summary of Glyclean™ D70 Efficacy Studies

Species

Guideline

Wt % Acid

% Reduction

E. coli

AOAC 955.14; 964.02

5.0% >99.999
E. coli O157:H7

AOAC 955.14; 964.02

5.0% >99.999
Listeria mono.

AOAC 955.14; 964.02

5.0% >99.999
Listeria welsh.

AOAC 955.14; 964.02

5.0% >99.999
Pseudomonas aer.

AOAC 955.14; 964.02

5.0% >99.999
Salmonella Chol.

AOAC 955.14; 964.02

5.0% >99.999
Salmonella typ.

AOAC 955.14; 964.02

5.0% >99.999
Staphylococcus aur.

AOAC 955.14; 964.02

5.0% >99.999
Herpes Simplex 1 EPA DIS/TSS-7 5.0% >99.99
Influenza A-2 EPA DIS/TSS-7 5.0% >99.99
Rhinovirus Type 37 EPA DIS/TSS-7 5.0% >99.99
SARS-CoV-2 ocspp 810.2200 5.5% >99.99

Summary of Broad-Spectrum Disinfectant and Cleaner Efficacy Studies

Species

Guideline

Wt % Acid

% Reduction

SARS-CoV-2

ocspp 810.2200

5.5% >99.99
Pseudomonas aer.

ocspp 810.2200

5.5% >99.99
Salmonella ent.

ocspp 810.2200

5.5% >99.99
Staphylococcus aur.

ocspp 810.2200

5.5% >99.99

Summary of Hard Surface Cleaner Efficacy Studies

Species

Guideline

Wt % Acid

% Reduction

SARS-CoV-2

ocspp 810.2200

5.0% >99.99
E. coli 

AOAC 955.14; 964.02

5.0% >99.999
Pseudomonas aer.

AOAC 955.14; 964.02

5.0% >99.999
Salmonella Chlor.

AOAC 955.14; 964.02

5.0% >99.999
Staphylococcus aur.

AOAC 955.14; 964.02

5.0% >99.999
Herpes Simplex 1

EPA DIS/TSS-7

5.0% >99.999
Influenza A-2 EPA DIS/TSS-7 5.0% >99.999
Rhinovirus Type 37 EPA DIS/TSS-7 5.0% >99.999

Summary of Pine Cleaner Efficacy Studies

Species

Guideline

Wt % Acid

% Reduction

Salmonella ent.

EPA DIS/TSS-7

2.1% >99.999
Staphylococcus aur.

AOAC 955.14; 964.02

2.1% >99.999
Influenza A

AOAC 955.14; 964.02

2.1% >99.999

Summary of Toilet Bowl Cleaner Efficacy Studies

Species

Guideline

Wt % Acid

% Reduction

E. coli

AOAC 955.14; 964.02

9.5% >99.999
Pseudomonas aer.

AOAC 955.14; 964.02

9.5% >99.999
Salmonella ent.

AOAC 955.14; 964.02

9.5% >99.999
Staphylococcus aur.

AOAC 955.14; 964.02

9.5% >99.999
Herpes Simplex 1 EPA DIS/TSS-7 9.5% >99.999
Influenza A-2 EPA DIS/TSS-7 9.5% >99.999
Rhinovirus Type 37 EPA DIS/TSS-7 9.5% >99.999

 

Glyclean™ European Efficacy Studies

 

Summary of Hard Surface Cleaner and Disinfectant Efficacy Studies

Species

Guideline

Wt % Acid

% Reduction

Enterococcus hirae

UNE-EN 1276; 13697

80%; 75% >99.9999
E. coli

UNE-EN 1276; 13697

80%; 75% >99.9999
Pseudomonas aer.

UNE-EN 1276; 13697

80%; 75% >99.9999
Staphylococcus aur.

UNE-EN 1276; 13697

80%; 75% >99.9999
Aspergillus brasil. UNE-EN 13697; A1 Full Strength >99.9999
Candida albicans UNE-EN 1650 60% >99.9999
Adenovirus NF EN 14476; A2 20% >99.9999
Murine norovirus NF EN 14476; A2 20% >99.9999
Poliovirus NF EN 14476; A2 20% >99.9999

Summary of Broad-Spectrum Disinfectant and Cleaner Efficacy Studies

Species

Guideline

Wt % Acid

% Reduction

Enterococcus hirae

UNE-EN 1276; 13697

60%; 50% >99.9999
E. coli

UNE-EN 1276; 13697

60%; 50% >99.9999
Pseudomonas aer.

UNE-EN 1276; 13697

60%; 50% >99.9999
Staphylococcus aur.

UNE-EN 1276; 13697; A1

60%; 50%; full strength >99.9999

EPA-Registered Glyclean™ D70 Disinfectant and Cleaning Formulations

 

  • Glyclean™ Hard Surface Cleaner (5% A.I.)
  • Glyclean™ Pine Cleaner (2.1% A.I.)
  • Glyclean™ Broad Spectrum Disinfectant & Cleaner (5.5% A.I., pending final approval)
  • Glyclean™ Toilet Bowl Cleaner (9.5% A.I., pending reformulation)

About Glyclean™:

 

Naturally Occurring Chemical

Glyclean™ D is a family of disinfecting products based upon the natural power of glycolic acid. Glycolic acid is the smallest of the fruit acids and is found in a wide variety of produce we eat daily. Its small size and unique chemistry make it a highly effective and efficient antimicrobial agent that is easy on the environment. Chemours glycolic acid is identical to the glycolic acid found in nature; it is synthesized similar to Glypure™ and other Chemours glycolic acid products by a highly efficient production process in the United States.

 

US EPA FIFRA Registrations

In the United States, Chemours supports the raw material EPA registration under FIFRA for glycolic acid. In addition, multiple product formulations are registered under FIFRA for sub-registration opportunities. Glyclean™ D70 has been approved for killing the SARS-CoV-2 virus, the cause of the COVID-19 pandemic. In addition, the Hard Surface Cleaner formulation label is registered with the US EPA and the California EPA for label claims against killing the SARS-CoV-2 virus.

 

    Global Registrations

    The Chemours Company provides Glyclean™ D regulatory support around the world. In the EU, the Glyclean™ D products can be utilized in formulations for national registrations. The BPR process offers a transition period that supports registering new formulations using Glyclean™ D. This assures that Glyclean™ D formulations will have long-term sustainability, meeting modern and future regulatory requirements. Glyclean™ D is currently found in formulations in Canada and many other countries worldwide.

     

    Sustainability and regulatory longevity of Glyclean™

    Chemours is the only glycolic acid supplier having or pursuing regulatory registrations globally: US EPA registration, Canada, EU BPR, GB BPR, and Korean BPR. Chemours is also the only glycolic acid manufacturer that has a dedicated technical service group supporting customers with formulation questions and regulatory needs.

    Chemours has 90 years of experience managing and running large volume glycolic acid production processes and a long track record of reliable supply to a wide range of customers and products. Glyclean™ is an excellent alternative to traditional disinfectants facing regulatory pressure, such as quaternary ammonium compounds or quats.

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