The personal care and cosmetics market is forcing formulators to select their preservatives from a limited number of acceptable antimicrobial chemistries. The pressure is rising, and the regulatory restrictions are driving the market towards greener and preservative-free formulations.
The EU region is also putting a lot of pressure on the preservatives that are allowed in personal care formulations. Only a few of the listed 59 actives are not under pressure or being reviewed at the moment.
Thus, PC formulators are seeking alternative methods of protection away from traditional preservatives. A new formulation approach is to use boosting ingredients and multifunctional materials that provide a primary function while offering antimicrobial efficacy as a secondary benefit. However, such ingredients struggle to deliver the required level of preservation and increase the product cost significantly.
Results show that the use of Glypure™ cosmetic grade glycolic acid allows you to decrease the level of preservatives or eliminate the need for preservation boosters in personal care and cosmetic products.
Glypure™ or Glycolic is an organic acid commonly used as an active ingredient or additive in skin and hair care products. Glypure™ is among the most popular actives in antiaging, skin lightening, acne treatments, and skin peeling formulations.
Organic acids have a long history of being used as food preservatives, making them more preferred and accepted by most consumers. They are also naturally occurring, have green chemistries, and are safer to use in skincare and cosmetic products. Thus, organic acids face minimal restrictions globally and are considered one of the safest alternatives to traditional preservatives.
Glypure™ Antimicrobial Efficacy
Glypure™ samples were tested by a third party and successfully met the passing criteria outlined in Chapter <51> of USP NF-2009. The testing was conducted at various concentrations and pH levels, outlined below are some of the testing results:
Evaluate the preservative efficacy of Glypure™ in formulations at concentrations of 1–8% and pH 3.5–4.2.
Glypure™ Skin Care Anti-Aging Serum.
Microorganisms used for testing include:
• Staphylococcus aureus
• Aspergillus brasiliensis
• Pseudomonas aeruginosa
• Candida albicans
• Escherichia coli
Test passing criteria for a category 2 product:
Bacteria to be no less than 2 log10 reductions from the initial count at 14 days and no increase from the 14 day count at 28 days.