Skip to main content

API Solvents

High-Purity API Solvents

The pharmaceutical industry is one of the most highly regulated markets in North America. As such, API manufacturing requires solvents with extremely high purities and consistency. Haltermann Carless has over 50 years of experience manufacturing premium hydrocarbon solvents for the pharmaceutical industry.

Importance of Solvents for API Manufacturing


APIs (active pharmaceutical ingredients) are active ingredients in pharmaceutical drugs that help improve or sustain health. Many different organic solvents are used during the manufacture of APIs and intermediates. Organic solvents are commonly used as reaction media during synthesis steps, purification, product washing, and cleaning equipment.
API solvents are chosen based on their physical properties, often by the solubility and boiling point. A common technique to purify APIs and pharmaceutical intermediates is via crystallization. During crystallization, the purified ingredient is soluble in the solvent at high temperatures, but has low solubility at room temperature.
Solvent purity is critical during API manufacturing. Manufacturers rely on quality, high-purity organic solvents to achieve efficient, controlled, and reproducible synthesis steps. Haltermann Carless manufactures hydrocarbon solvents with purity standards up to 99.75%. Because of their many years of expertise in high-purity solvents, many leading API manufacturers choose to work with Haltermann Carless for their solvent needs.

Haltermann-High Purity Hydrocarbon Solvents

Manufacturers can produce high-quality and effective APIs with Haltermann Carless high-purity hydrocarbon solvents. Below are the advantages of using a Haltermann high-purity hydrocarbon.
  • High-purity grades from 95% to 99.75%
  • Consistent and reliable quality
  • Wide selection of hydrocarbon solvents
  • Production process complies with GMP standards
  • ISO 9001 and ISO 14001 certified
  • Can provide individualized quality parameters in some cases

The Haltermann Carless product portfolio includes the following hydrocarbons commonly used in API manufacturing:


Get a Sample

PHONE  425.372.9328

Hi, let us know if you have any questions as you visit our website.

ChemPoint reps are here to assist you