We apologize! The document was not able to download due to an unknown error. Our team has been notified and we will fix it as soon as possible. Fill out the form below, and we will send you the document as soon as we can!
SYLOID® 244 FP
SYLOID® 244 FP is a unique synthetic silica excipient containing an amorphous silicon dioxide, chemically prepared by GRACE. Formulated with a high pore volume of 1.5 ml/g and a large internal surface area, SYLOID® 244 FP is suitable for a range of applications in pharmaceuticals and nutraceuticals.
SYLOID® 244 FP is a high-pore volume silica excipient that provides multifunctional benefits and functionality across industries. Its outstanding porosity, absorption, density, particle size distribution, and internal surface area, ensure optimal performance, reducing the number of excipients needed and minimizing the complexity of formulations with maximum dosage efficacy. In pharmaceuticals and personal care, it provides excellent moisture protection and anti-tacking properties for glidant functionality and can be used as a suspension aid in tablet coating formulations. Its exceptional compatibility with active ingredients ensures versatile formulating capabilities as a glidant, tableting aid, and carrier, SYLOID® 244 FP can absorb up to 1.6 mL of liquid per gram with a strong affinity for moisture and organic base liquids.
Specifications
Appearance: Powder Color: White Loss on ignition (1832°F): 8.5% max. Loss on drying (145°C): 5.0% max. SiO₂ content (dry basis): 99.0% min Sulfate (SO₄): 0.5% max Iron (Fe₂O₃): 200 ppm max. pH (5% slurry): 5.0─8.0 pH – EP (5%): 4.0─7.0 Average particle size malvern® Mastersizer® 2000: 5─7 µm Oil adsorption: 300 g/100g Pore volume (N₂): 1.5 ml/g Sodium oxide (Na₂O) ≤0.2 wt. % Sodium sulfate (Na₂SO₄): ≤1.5 wt. % Aluminum oxide (Al₂O₃): 0.2 wt. % max. Calcium oxide (CaO): 0.14 wt. % max. Chlorides (Cl): 0.1 wt. % max. CAS no. 7631-86-9
Primary Chemistry: Amorphous silicon dioxide
Features & Benefits
Amorphous silicon dioxide Multifunctional excipient Free-flow additive High purity Improve manufacturing efficiency, dissolution, therapeutic effectiveness, and stability Moisture protection Reduces electrostatic charging Improves flow properties Moisture-assisted dry granulation Excellent compatibility with actives Oil absorption properties in lipid-based technologies Prevents valve blockage in direct compression Highly defined pore structures Excellent porosity and particle size distribution Enhanced moisture protection Anti-sticking and anti-tacking Absorbs up to 1.5 ml of liquid per gram Matting agent Anti-caking Prevents clumping Viscosity control
Problems Solved
Valve blockage in direct compression applications
Applications
APIs Nutraceutical extracts Film coatings Sublingual and effervescent tablets
ChemPoint will not under any circumstances release personal user information to individuals or companies. All information collection is solely used to support ChemPoint customers service communications. Read our Privacy Notice.
Thank you
Thank you for your inquiry and interest in ChemPoint. We will respond to you shortly.
ChemPoint will not under any circumstances release personal user information to individuals or companies. All information collection is solely used to support ChemPoint customers service communications. Read our Privacy Notice.
Thank you
Thank you for your inquiry and interest in ChemPoint. We will respond to you shortly.
ChemPoint will not under any circumstances release personal user information to individuals or companies. All information collection is solely used to support ChemPoint customers service communications. Read our Privacy Notice.
Document Download
The document currently is provided in the following languages from the supplier at this time.
Document Download
The document currently is provided in the following languages from the supplier at this time.
Are you in the correct region?
We’ve detected that you are located in a different region than the region selected on the website. Would you like to change your region?
Current Region:
English - United States
Hi, let us know if you have any questions as you visit our website.
