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SYLOID® XDP 3050
SYLOID® XDP 3050 is a high-performance silicon dioxide-based excipient agent used in the formulation of pharmaceuticals and nutraceuticals. Its controlled particle size and high porosity makes it the ideal carrier for lipids.
SYLOID® XDP 3050 is a synthetic amorphous silica containing a high-purity silicon dioxide with superior stability. Specially engineered to be a high-performance lipid carrier with excellent absorption properties, SYLOID® XDP 3050 effectively transforms liquids, such as oily actives and lipid-based systems, to free-flowing solids and allows nutraceutical formulators to achieve solid dosage forms with liquid ingredients. Its specific pore size and bulk density of 275 g/l ensure optimal drug load or lipid delivery in a given volume for table or capsule pharmaceuticals.
Specifications
Appearance: Powder Color: White Loss on ignition (USP, 1000°F, 1 h): 8.5% max. Loss on drying (USP, 145°C, 4 h): 5.0% max. SiO₂ content (dry basis): 99.0% min Sulfate (SO₄): 0.5% max pH (USP, 5 % aqueous suspension): 4.0─8.0 pH (EP): 4.0─7.0 Average particle size malvern® Mastersizer®: 48─66 µm Specific Surface Area (BET): 320 m²/g Oil absorption (linseed oil): 300 g/100 g Tapped bulk density: 275 g/l Chlorides (Cl) dry basis, USP: 0.1 % max. Mercury (Hg): 0.1 mg/kg max. Iron Oxide (Fe₂O₃) dry basis: 0.03% max. Sodium oxide (Na₂O) dry basis 0.15% max Calcium Oxide (CaO): 0.14 % max. Water Absorption (EP): yes Substances soluble in HCl (EP): 10.0 mg max. Arsenic (As): 0.5 mg/kg max. Cadmium (Cd): 0.5 mg/kg max. Lead (Pb): 1.0 mg/kg max. Total aerobic plate count: 1000 cfu/g CAS no. 7631-86-9
Primary Chemistry: Amorphous silicon dioxide
Features & Benefits
Amorphous silicon dioxide Multifunctional excipient Maximum load capacity Excellent release and bioavailability Free-flow additive High purity Improve manufacturing efficiency, dissolution, therapeutic effectiveness, and stability Moisture protection Reduces electrostatic charging Improves flow properties Moisture-assisted dry granulation Excellent compatibility with actives Oil absorption properties in lipid-based technologies Prevents valve blockage in direct compression Highly defined pore structures Excellent porosity and particle size distribution Enhanced moisture protection Anti-sticking and anti-tacking Absorbs up to 1.5 ml of liquid per gram Matting agent Anti-caking Prevents clumping Viscosity control
Problems Solved
Valve blockage in direct compression applications
Applications
APIs Pharmacuetical products Nutraceutical extracts Film coatings Sublingual and effervescent tablets Liquisolid pharmaceuticals
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Thank you for your inquiry and interest in ChemPoint. We will respond to you shortly.
ChemPoint will not under any circumstances release personal user information to individuals or companies. All information collection is solely used to support ChemPoint customers service communications. Read our Privacy Notice.
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