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RESOMER® RG 502
RESOMER® RG 502 is a lactide-based solvent-purified copolymer containing a 50:50 ratio of D,L-lactide and glycolide with an alkyl ester end group. Available as a white to off-white granule powder, RESOMER® RG 502 has an inherent viscosity of 0.16─0.24 dL/g and a degradation time of 3 months.
RESOMER® RG 502 is a specialized pharmaceutical controlled-release agent designed for use with complex parenteral drug products, microparticles, in-situ depot formulations, drug-loaded implants, and long-acting medication systems. Formulated by Evonik with a 50:50 blend of D,L-lactide and glycolide, it is a bioabsorbable and biodegradable polymer that is readily absorbed by the body. The inherent viscosity of RESOMER® RG 502, 0.16─0.24 dL/g, influences its mechanical properties and degradation rate with a max of 3 months degradation time.
RESOMER® polymers have been purified for a reduced residual monomer content and are available in a variety of molecular weights and viscosity ranges to meet application needs. All polymer properties can also be adjusted to match formulation requirements.
Specifications
Physical state: Solid Form: Powder granules Color: White to off-white Inherent viscosity (dl/g): 0.16─0.24 Degradation time: <3 months CAS No. 26780-50-7
Primary Chemistry: Poly(D,L-lactide-co-glycolide)
Features & Benefits
Solvent-purified co-polymer 50:50 D,L-lactide:Glycolide ratio 3 month degradation period Bioabsorbable Biodegradable Processed by injection molding Completely metabolized by the body Ideal for terminal sterilization Suitable for use with small molecules, peptides, proteins, and other substances
Problems Solved
Applications
Controlled release applications Microparticles and drug-loaded implants Long acting medication delivery formulations
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