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RESOMER® RG 502 H
RESOMER® RG 502 H is an acid-terminated version of RESOMER® RG 502 lactide-based polymer for pharmaceutical controlled release. RESOMER® RG 502 H is composed of 50 mol % D,L-lactide and 50 mol % glycolide.
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- Manufacturer: Evonik Corporation
- Product Line: RESOMER® Polymers
- Product: RESOMER® RG Polymers
- Industries: Pharmaceuticals
- Authorized Countries: Canada | United States
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Canada
United States
Overview
RESOMER® RG 502 H is a carefully formulated lactide-based copolymer containing a 50:50 ratio of D,L-lactide and glycolide with a free carboxylic acid end group. It is designed for the controlled release of peptides, proteins, small molecules, and other substances in complex parenteral drug products, microparticles, in-situ depot formulations, drug-loaded implants, and long-acting medication systems.
RESOMER® polymers have been purified for a reduced residual monomer content and are available in various molecular weights and viscosity ranges to meet application needs. All polymer properties can also be adjusted to match formulation requirements.
Specifications
Physical state: Solid
Form: Powder granules
Color: White to off-white
Inherent viscosity (dl/g): 0.16─0.24
Degradation time: <3 months
CAS No. 26780-50-7
Primary Chemistry: Poly(D,L-lactide-co-glycolide)
Features & Benefits
- Solvent-purified co-polymer
- 50:50 D,L-lactide:Glycolide ratio
- Free carboxylic acid terminated
- 3 month degradation period
- Bioabsorbable
- Biodegradable
- Processed by injection molding
- Completely metabolized by the body
- Ideal for terminal sterilization
- Suitable for use with small molecules, peptides, proteins, and other substances
Applications
Controlled release applications Microparticles and drug-loaded implants Long acting medication delivery formulations
Related Applications
Pharmaceuticals
Related Functions
Pharmaceuticals
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