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RESOMER® RG 503
RESOMER® RG 503 is a biodegradable and bioresorbable lactide copolymer powder with an inherent viscosity viscosity of 0.32-0.44 dL/g. It is composed of 50 mol % D,L-lactide and 50 mol % glycolide and is recommeded for parenteral controlled release of pharmaceutical substances.
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- Manufacturer: Evonik Corporation
- Product Line: RESOMER® Polymers
- Product: RESOMER® RG Polymers
- Industries: Pharmaceuticals
- Authorized Countries: Canada | United States
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Canada
United States
Overview
RESOMER® RG 503 is a medium-viscosity, alkyl ester terminated RESOMER® polymer granular powder from Evonik formulated with an inherent viscosity range of 0.32-0.44 dL/g and a degradation time of 3 months. This lactide polymer provides speciaty delayed release capabilities ensuring the controlled release of microparticles, small molecules, peptides, proteins, and more in long-acting medication delivery systems, in-situ depot formlations, and drug-loaded implants. RESOMER® RG 503 contains a solvent-purified combination of 50 mol % D,L-lactide and 50 mol % glycolide to achieve a low residual monomer content.
RESOMER® RG 503 complies with FDA, GMP, EHS, DIN ISO 9001, MAF, and DMF regulations.
RESOMER® polymers have been purified for a reduced residual monomer content and are available in a variety of molecular weights and viscosity ranges to meet application needs. All polymer properties can also be adjusted to match formulation requirements.
Specifications
Physical state: Solid
Form: Powder granules
Color: White to off-white
Inherent viscosity (dl/g): 0.32─0.44
Degradation time: <3 months
CAS No. 26780-50-7
Primary Chemistry: Poly(D,L-lactide-co-glycolide)
Features & Benefits
- Solvent-purified co-polymer
- 50:50 D,L-lactide:Glycolide ratio
- Alkyl ester terminated
- 3 month degradation period
- Bioabsorbable
- Biodegradable
- Processed by injection molding
- Completely metabolized by the body
- Ideal for terminal sterilization
- Suitable for use with small molecules, peptides, proteins, and other substances.
Applications
Controlled release applications Microparticles and drug-loaded implants Long acting medication delivery formulations
Related Applications
Pharmaceuticals
Related Functions
Pharmaceuticals
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