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RESOMER® RG 503
RESOMER® RG 503 is a biodegradable and bioresorbable lactide copolymer powder with an inherent viscosity viscosity of 0.32-0.44 dL/g. It is composed of 50 mol % D,L-lactide and 50 mol % glycolide and is recommeded for parenteral controlled release of pharmaceutical substances.
Fulfilled By ChemPoint
- Manufacturer: Evonik Corporation
- Product Line: RESOMER® Polymers
- Product: RESOMER® RG Polymers
- Industries: Pharmaceuticals
- Authorized Countries: Canada | United States
Fulfilled By ChemPoint
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Overview
RESOMER® RG 503 is a medium-viscosity, alkyl ester terminated RESOMER® polymer granular powder from Evonik formulated with an inherent viscosity range of 0.32-0.44 dL/g and a degradation time of 3 months. This lactide polymer provides speciaty delayed release capabilities ensuring the controlled release of microparticles, small molecules, peptides, proteins, and more in long-acting medication delivery systems, in-situ depot formlations, and drug-loaded implants. RESOMER® RG 503 contains a solvent-purified combination of 50 mol % D,L-lactide and 50 mol % glycolide to achieve a low residual monomer content.
RESOMER® RG 503 complies with FDA, GMP, EHS, DIN ISO 9001, MAF, and DMF regulations.
RESOMER® polymers have been purified for a reduced residual monomer content and are available in a variety of molecular weights and viscosity ranges to meet application needs. All polymer properties can also be adjusted to match formulation requirements.
Specifications
Physical state: Solid
Form: Powder granules
Color: White to off-white
Inherent viscosity (dl/g): 0.32─0.44
Degradation time: <3 months
CAS No. 26780-50-7
Primary Chemistry: Poly(D,L-lactide-co-glycolide)
Features & Benefits
Solvent-purified co-polymer
50:50 D,L-lactide:Glycolide ratio
Alkyl ester terminated
3 month degradation period
Bioabsorbable
Biodegradable
Processed by injection molding
Completely metabolized by the body
Ideal for terminal sterilization
Suitable for use with small molecules, peptides, proteins, and other substances.
Applications
Controlled release applications
Microparticles and drug-loaded implants
Long acting medication delivery formulations
Related Applications
Pharmaceuticals
Related Functions
Pharmaceuticals
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