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RESOMER® RG 503
RESOMER® RG 503 is a biodegradable and bioresorbable lactide copolymer powder with an inherent viscosity viscosity of 0.32-0.44 dL/g. It is composed of 50 mol % D,L-lactide and 50 mol % glycolide and is recommeded for parenteral controlled release of pharmaceutical substances.
RESOMER® RG 503 is a medium-viscosity, alkyl ester terminated RESOMER® polymer granular powder from Evonik formulated with an inherent viscosity range of 0.32-0.44 dL/g and a degradation time of 3 months. This lactide polymer provides speciaty delayed release capabilities ensuring the controlled release of microparticles, small molecules, peptides, proteins, and more in long-acting medication delivery systems, in-situ depot formlations, and drug-loaded implants. RESOMER® RG 503 contains a solvent-purified combination of 50 mol % D,L-lactide and 50 mol % glycolide to achieve a low residual monomer content.
RESOMER® RG 503 complies with FDA, GMP, EHS, DIN ISO 9001, MAF, and DMF regulations.
RESOMER® polymers have been purified for a reduced residual monomer content and are available in a variety of molecular weights and viscosity ranges to meet application needs. All polymer properties can also be adjusted to match formulation requirements.
Specifications
Physical state: Solid Form: Powder granules Color: White to off-white Inherent viscosity (dl/g): 0.32─0.44 Degradation time: <3 months CAS No. 26780-50-7
Primary Chemistry: Poly(D,L-lactide-co-glycolide)
Features & Benefits
Solvent-purified co-polymer 50:50 D,L-lactide:Glycolide ratio Alkyl ester terminated 3 month degradation period Bioabsorbable Biodegradable Processed by injection molding Completely metabolized by the body Ideal for terminal sterilization Suitable for use with small molecules, peptides, proteins, and other substances.
Applications
Controlled release applications Microparticles and drug-loaded implants Long acting medication delivery formulations
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