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RESOMER® RG 503 H is an acid-terminated version of RESOMER® RG 503 lactide copolymer containing a blend of 50 mol % D,L-Lactide and 50 mol % Glycolide for pharmaceutical controlled release. RESOMER® RG 503 H has an inherent viscosity viscosity of 0.32-0.44 dL/g and is recommended for processing by injection molding.
RESOMER® RG 503 H is a bioabsorbable parenteral excipient recommended for pharmaceutical applications, providing exceptional controlled release capabilities and long-term stability with a maximum of 3 months degradation time. This lactide polymer has a standard mole ration of 50:50 D,L-lactide and glycolide and has been solvent purified to reduce the products residual monomer content.
RESOMER® RG 503 complies with FDA, GMP, EHS, DIN ISO 9001, MAF, and DMF regulations.
RESOMER® polymers have been purified for a reduced residual monomer content and are available in a variety of molecular weights and viscosity ranges to meet application needs. All polymer properties can also be adjusted to match formulation requirements.
Physical state: Solid
Form: Powder granules
Color: White to off-white
Inherent viscosity (dl/g): 0.32─0.44
Degradation time: <3 months
CAS No. 26780-50-7
Primary Chemistry: Poly(D,L-lactide-co-glycolide)
Solvent-purified co-polymer
50:50 D,L-lactide:Glycolide ratio
Free carboxylic acid terminated
3 month degradation period
Bioabsorbable
Biodegradable
Processed by injection molding
Completely metabolized by the body
Ideal for terminal sterilization
Suitable for use with small molecules, peptides, proteins, and other substances
Controlled release applications
Microparticles and drug-loaded implants
Long acting medication delivery formulations
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