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RESOMER® RG 503 H
RESOMER® RG 503 H is an acid-terminated version of RESOMER® RG 503 lactide copolymer containing a blend of 50 mol % D,L-Lactide and 50 mol % Glycolide for pharmaceutical controlled release. RESOMER® RG 503 H has an inherent viscosity viscosity of 0.32-0.44 dL/g and is recommended for processing by injection molding.
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- Manufacturer: Evonik Corporation
- Product Line: RESOMER® Polymers
- Product: RESOMER® RG Polymers
- Industries: Pharmaceuticals
- Authorized Countries: Canada | United States
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Canada
United States
Overview
RESOMER® RG 503 H is a bioabsorbable parenteral excipient recommended for pharmaceutical applications, providing exceptional controlled release capabilities and long-term stability with a maximum of 3 months degradation time. This lactide polymer has a standard mole ration of 50:50 D,L-lactide and glycolide and has been solvent purified to reduce the products residual monomer content.
RESOMER® RG 503 complies with FDA, GMP, EHS, DIN ISO 9001, MAF, and DMF regulations.
RESOMER® polymers have been purified for a reduced residual monomer content and are available in a variety of molecular weights and viscosity ranges to meet application needs. All polymer properties can also be adjusted to match formulation requirements.
Specifications
Physical state: Solid
Form: Powder granules
Color: White to off-white
Inherent viscosity (dl/g): 0.32─0.44
Degradation time: <3 months
CAS No. 26780-50-7
Primary Chemistry: Poly(D,L-lactide-co-glycolide)
Features & Benefits
- Solvent-purified co-polymer
- 50:50 D,L-lactide:Glycolide ratio
- Free carboxylic acid terminated
- 3 month degradation period
- Bioabsorbable
- Biodegradable
- Processed by injection molding
- Completely metabolized by the body
- Ideal for terminal sterilization
- Suitable for use with small molecules, peptides, proteins, and other substances
Applications
Controlled release applications Microparticles and drug-loaded implants Long acting medication delivery formulations
Related Applications
Pharmaceuticals
Related Functions
Pharmaceuticals
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