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RESOMER® RG 504 H
RESOMER® RG 504 H is a solvent-purified poly(D,L-lactide-co-glycolide) polymer with an acid end group and inherent viscosity of 0.45-0.60 dL/g. RESOMER® RG 504 H has a degradation period of 3 months maximum.
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- Manufacturer: Evonik Corporation
- Product Line: RESOMER® Polymers
- Product: RESOMER® RG Polymers
- Industries: Pharmaceuticals
- Authorized Countries: Canada | United States
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Canada
United States
Overview
RESOMER® RG 504 H is an acid-terminated version of RESOMER® RG 504 poly(D,L-lactide-co-glycolide) copolymer containing a blend of 50 mol % D,L-Lactide and 50 mol % Glycolide for pharmaceutical controlled release. This lactide polymer provides specialty delayed release capabilities ensuring the controlled release of peptides, microparticles, small molecules, proteins, and more in in-situ depot formulations, long-acting medication delivery systems, and drug-loaded implants.
RESOMER® RG 504 H complies with FDA, GMP, EHS, DIN ISO 9001, MAF, and DMF regulations.
RESOMER® polymers have been purified for a reduced residual monomer content and are available in a variety of molecular weights and viscosity ranges to meet application needs. All polymer properties can also be adjusted to match formulation requirements.
Specifications
Physical state: Solid
Form: Powder granules
Color: Various
Inherent viscosity (dl/g): 0.45─0.60
Degradation time: <3 months
CAS No. 26780-50-7
Primary Chemistry: Poly(D,L-lactide-co-glycolide)
Features & Benefits
- Solvent-purified co-polymer
- 50:50 D,L-lactide:Glycolide ratio
- Free carboxylic acid terminated
- 3-month degradation period
- Bioabsorbable
- Biodegradable
- Processed by injection molding
- Completely metabolized by the body
- Ideal for terminal sterilization
- Suitable for use with small molecules, peptides, proteins, and other substances
Applications
Controlled release applications Microparticles and drug-loaded implants Long acting medication delivery formulations
Related Applications
Pharmaceuticals
Related Functions
Pharmaceuticals
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