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RESOMER® RG 505
RESOMER® RG 505 is a high-viscosity lactide-based copolymer with an alkyl ester end group. Specially formulated by Evonik to provide controlled drug release in pharmaceutical applications, this copolymer offers excellent substance compatibility and has a degredation time of 3 months maximum.
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- Manufacturer: Evonik Corporation
- Product Line: RESOMER® Polymers
- Product: RESOMER® RG Polymers
- Industries: Pharmaceuticals
- Authorized Countries: Canada | United States
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Authorized Countries
Canada
United States
Overview
RESOMER® RG 505 is a biodegradable polymer commonly used in controlled-release pharmaceutical applications, such as in-situ depot formulations, long-acting medication delivery systems, and drug-loaded implants. It is composed of a blend of 50 mol % D,L-Lactide and 50 mol % Glycolide with a high inherent viscosity of 0.61─0.74 dL/g. It is also compatible with a wide range of medical substances, peptides, microparticles, small molecules, and proteins for versatility.
RESOMER® RG 505 complies with FDA, GMP, EHS, DIN ISO 9001, MAF, and DMF regulations.
RESOMER® polymers have been purified for a reduced residual monomer content and are available in various molecular weights and viscosity ranges to meet application needs. All polymer properties can also be adjusted to match formulation requirements.
Specifications
Physical state: Solid
Form: Powder granules
Color: White to off-white
Inherent viscosity (dl/g): 0.61─0.74
CAS No. 26780-50-7
Primary Chemistry: Poly(D,L-lactide-co-glycolide)
Features & Benefits
- Solvent-purified co-polymer
- 50:50 D,L-lactide:Glycolide ratio
- Alkyl ester terminated
- 3-month degradation period
- Bioabsorbable
- Biodegradable
- Processed by injection molding
- Completely metabolized by the body
- Ideal for terminal sterilization
- Suitable for use with small molecules, peptides, proteins, and other substances
Applications
Controlled release applications Microparticles and drug-loaded implants Long acting medication delivery formulations
Related Applications
Pharmaceuticals
Related Functions
Pharmaceuticals
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