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RESOMER® RG 653 H
RESOMER® RG 653 H is a high-quality controlled release agent for pharmaceutical applications. It contains a 65:35 blend of d,l-lactide and glycolide with an acid end group and an inherent viscosity of 0.32─0.44 dL/g.
RESOMER® RG 653 H is a bioresorbable excipient from Evonik, formulated for the contolled release of pharmaceutical substances, small molecules, proteins, and more in complex parenteral drug products, such as in-situ depot formulations, long-acting medication delivery systems, and drug-loaded implants. Composed of a blend of 65 mol % D,L-Lactide and 35 mol % Glycolide, RESOMER® RG 653 H complies with FDA, GMP, EHS, DIN ISO 9001, MAF, and DMF regulations.
RESOMER® polymers have been purified for a reduced residual monomer content and are available in various molecular weights and viscosity ranges to meet application needs. All polymer properties can also be adjusted to match formulation requirements.
Specifications
Physical state: Solid Form: Powder granules Color: White to off-white Inherent viscosity (dl/g): 0.32─0.44 Degradation time: <3 months CAS No. 26780-50-7
Primary Chemistry: Poly(D,L-lactide-co-glycolide)
Features & Benefits
Solvent-purified co-polymer 65:35 D,L-lactide:Glycolide ratio Free carboxylic acid terminated 3-month degradation period Bioabsorbable Biodegradable Processed by injection molding Completely metabolized by the body Ideal for terminal sterilization Suitable for use with small molecules, peptides, proteins, and other substances
Applications
Controlled release applications Microparticles and drug-loaded implants Long acting medication delivery formulations
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