Select Your Region
LACTEL® 50:50 DL-PLGE, IV 0.55-0.75
LACTEL® 50:50 DL-PLGE, IV 0.55-0.75 is a non-GMO pharmaceutical excipient with a polymer composition of 50 mol % D,L-lactide and 50 mol % Glycolide with an ester end group and no added preservatives. It is formulated by Evonik as a white to tan pelletized solid with an inherent viscosity of 0.55─0.75 dL/g in HFIP and a degradation time of 3 months max.
Quantity
Documents
- Manufacturer: Evonik Corporation
- Product Line: LACTEL® Polymers
- Product: LACTEL® PLGE Polymers
- Industries: Pharmaceuticals
- Authorized Countries: Canada | United States
Fulfilled By ChemPoint
Fulfilled By ChemPoint
Manufacturer
Product Line
Product
Industries
Authorized Countries
Canada
United States
Overview
LACTEL® 50:50 DL-PLGE, IV 0.55-0.75 is a 100% bioresorbable PLGA-based copolymer containing a 50:50 mol ratio of D,L-Lactide and Glycolide, providing a uniform degredation rate of 3 months for controlled drug delivery. It is compatible with a range of pharmaceutical substance types, including peptides, proteins, nanoparticles, and microparticles for the formulation of long-acting injectable formulations in veterinary medicine and human generic drug formulations. As a non-solvent purified poly (D,L-lactide-co-glycolide) polymer with an amorphous nature, it exhibits enhanced adaptability and versatility in formulations with superior stability properties. LACTEL® 50:50 DL-PLGE, IV 0.55-0.75 is non-GMO certified and has no added preservatives.
Specifications
Physical state: Solid
Form: Granules
Color: White to light tan
Inherent viscosity (IV) dL/g: 0.55─0.75 (in HFIP)
Degradation time: <3 months
Crystalline Melt Transition (°C): Amorphous
Glass transition temp (°C): 45─50
Solubility (@ 5% w/w): Dichloromethane, tetrahydrofuran, ethyl acetate, chloroform, hexafluoroisopropanol, acetone
Approx. resorption (months): 1─2
Density (g/mL): 1.34
Tensile Strength (psi): 6000─8000
Elongation (%): 3─10
Modulus (psi): 2─4x10⁵
CAS No. 26780-50-7
Primary Chemistry:
Poly(DL-lactide-co-glycolide)
Features & Benefits
- 50:50 ratio of D,L-Lactide and Glycolide
- Ester end group
- 3-month degradation time
- Biodegradable
- Ideal for terminal sterilization
- Bioabsorbable excipient
- Suitable for use with small molecules, peptides, proteins, and other substances
- Non-GMO
- No added preservatives
- Cost effective
Applications
Human generic drug formulations
Long-acting injectable formulations
Price sensitive applications
veterinary medicine
Related Applications
Pharmaceuticals
Related Functions
Pharmaceuticals
Have questions? Can't find the right product?
Ask our Experts
Have questions? Can't find the right product?
Ask our ExpertsWhen You're Ready
When You're Ready
View Support Articles
Talk to an Expert
Ask a Question
Are you in the correct region?
We’ve detected that you are located in a different region than the region selected on the website. Would you like to change your region?
Current Region: English - United States
