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LACTEL® 50:50 DL-PLGE, IV 0.55-0.75
LACTEL® 50:50 DL-PLGE, IV 0.55-0.75 is a non-GMO pharmaceutical excipient with a polymer composition of 50 mol % D,L-lactide and 50 mol % Glycolide with an ester end group and no added preservatives. It is formulated by Evonik as a white to tan pelletized solid with an inherent viscosity of 0.55─0.75 dL/g in HFIP and a degradation time of 3 months max.
LACTEL® 50:50 DL-PLGE, IV 0.55-0.75 is a 100% bioresorbable PLGA-based copolymer containing a 50:50 mol ratio of D,L-Lactide and Glycolide, providing a uniform degredation rate of 3 months for controlled drug delivery. It is compatible with a range of pharmaceutical substance types, including peptides, proteins, nanoparticles, and microparticles for the formulation of long-acting injectable formulations in veterinary medicine and human generic drug formulations. As a non-solvent purified poly (D,L-lactide-co-glycolide) polymer with an amorphous nature, it exhibits enhanced adaptability and versatility in formulations with superior stability properties. LACTEL® 50:50 DL-PLGE, IV 0.55-0.75 is non-GMO certified and has no added preservatives.
50:50 ratio of D,L-Lactide and Glycolide Ester end group 3-month degradation time Biodegradable Ideal for terminal sterilization Bioabsorbable excipient Suitable for use with small molecules, peptides, proteins, and other substances Non-GMO No added preservatives Cost effective
Applications
Human generic drug formulations Long-acting injectable formulations Price sensitive applications veterinary medicine
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