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LACTEL® DL-PLE, IV 0.55-0.75
LACTEL® DL-PLE, IV 0.55-0.75 is a non-GMO pharmaceutical excipient with a poly(DL-lactide) (CAS No. 26680-10-4) polymer composition and an inherent viscosity of 0.55─0.75 dL/g in chloroform.
Documents
- Manufacturer: Evonik Corporation
- Product Line: LACTEL® Polymers
- Product: LACTEL® PLE Polymers
- Industries: Pharmaceuticals
- Authorized Countries: Canada | United States
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United States
Overview
LACTEL® DL-PLE, IV 0.55-0.75 is a high-performance amorphous polymer containing poly(D,L-lactide) with an ester end group and no added preservatives. It is available as a white to yellowish granule solid pellet with an inherent viscosity of 0.55─0.75 dL/g in chloroform. As a pharmaceutical drug excipient, it provides a cost-effective solution for controlled drug delivery in veterinary medicine and human generic drug formulations, with wide substance compatibility, including peptides, proteins, microparticles, and nanoparticles. Formulated with 100% bioabsorbability, it is fully metabolized by the body for exceptional effectiveness with a degradation period of 12 months.
Specifications
Physical state: Solid
Form: Granules or pellets
Color: White to yellowish
Inherent viscosity (IV) dL/g: 0.55─0.75 (in chloroform)
Degradation time: <18 months
Crystalline Melt Transition (°C): Amorphous
Glass transition temp (°C): 50─60
Solubility (@ 5% w/w): Dichloromethane, tetrahydrofuran, ethyl acetate, chloroform, hexafluoroisopropanol, acetone
Approx. resorption (months): 12─16
Density (g/mL): 1.25
Tensile Strength (psi): 4000─6000
Elongation (%): 3─10
Modulus (psi): 2─4x10⁵
Density (g/mL): 1.25
Tensile Strength (psi): 4000─6000
Elongation (%): 3─10
Modulus (psi): 2─4x10⁵
CAS no. 26680-10-4
Primary Chemistry: Poly(DL-lactide)
Features & Benefits
- D,L-Lactide homopolymer
- Ester end group
- No added preservatives
- Bioabsorbable excipient
- Suitable for use with small molecules, peptides, proteins, and other substances
- Unpurified
- Cost-effective
- Non-GMO
Applications
Human generic drug formulations Long-acting injectable formulations Price sensitive applications veterinary medicine
Related Applications
Pharmaceuticals
Related Functions
Pharmaceuticals
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