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LACTEL 75:25 DL-PLGA, IV 0.70-0.90
LACTEL® 75:25 DL-PLGA, IV 0.70-0.90 is an acid-terminated polymeric drug delivery material made up of a 75:25 ratio of D,L-lactide and glycolide. It has a degradation rate of 3 months and an inherent viscosity of 0.70─0.90 dL/g in chloroform.
Documents
- Manufacturer: Evonik Corporation
- Product Line: LACTEL® Polymers
- Product: LACTEL® PLGA Polymers
- Industries: Pharmaceuticals
- Authorized Countries: Canada | United States
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Canada
United States
Overview
LACTEL® 75:25 DL-PLGA, IV 0.70-0.90 is a biodegradable and biocompatible synthetic copolymer with a composition of 75 mol % D,L-lactide and 25 mol % Glycolide with an acid end group. Properties such as the inherent viscosity of 0.70─0.90 dL/g in chloroform and degradation rate of 6 months have been optimized to fit the need of a specific release system with optimal metabolization in the body. LACTEL® 75:25 DL-PLGA, IV 0.70-0.90 can be used to release a wide range of small molecule drugs, peptides, and proteins in veterinary medicine and human generic drug formulations providing controlled drug delivery capabilities.
Specifications
Physical state: Solid
Form: Granules or pellets
Color: White to yellowish, off-white to light tan
Inherent viscosity (IV) dL/g: 0.70─0.90 (in chloroform)
Degradation time: <6 months
Density (g/mL): 1.34
Tensile Strength (psi): 6000─8000
Elongation (%): 3─10
Modulus (psi): 2─4x10⁵
CAS no. 26780-50-7
Primary Chemistry: Poly(DL-lactide-co-glycolide)
Features & Benefits
- 75:25 ratio of D,L-Lactide and Glycolide
- Acid end group
- No added preservatives
- Non-GMO
- Amorphous
- 6 month degradation period
- Bioabsorbable excipient
- Suitable for use with small molecules, peptides, proteins, and other substances
- Unpurified
- Cost-effective
- Non-GMO
Applications
Human generic drug formulations Long-acting injectable formulations Price sensitive applications veterinary medicine
Related Applications
Pharmaceuticals
Related Functions
Pharmaceuticals
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