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LACTEL® 50:50 DL-PLGE, IV 0.76-0.94
LACTEL® 50:50 DL-PLGE, IV 0.76-0.94 is an ester-terminated lactide-glycolide-containing copolymer (CAS No. 26780-50-7) with an inherent viscosity of 0.76─0.94 dL/g in HFIP and a degradation time of 3 months max.
Evonik's LACTEL® 50:50 DL-PLGE, IV 0.76-0.94 is a versatile pellatized excipient polymer with an ester terminated lactide-glycolide base with a mol ratio of 50:50. Manufactured using a streamlined process to produce a cost-effective PLGA copolymer, Evonik's LACTEL® 50:50 DL-PLGE, IV 0.76-0.94 is non-solvent purified and formulated with no-added preservatives. It is commonly recommended for use in the formulation of long-acting injectable formulations in veterinary medicine and human generic drug formulations, exhibiting excellent compatibility with a range of pharmaceutical substance types, including peptides, proteins, nanoparticles, and microparticles.
Specifications
Physical state: Solid Form: Granules Color: White to light tan Inherent viscosity (IV) dL/g: 0.76─0.94 (in HFIP) Degradation time: <3 months Density (g/mL): 1.34 Tensile Strength (psi): 6000─8000 Elongation (%): 3─10 Modulus (psi): 2─4x10⁵ CAS No. 26780-50-7
Primary Chemistry: Poly(DL-lactide-co-glycolide)
Features & Benefits
50:50 ratio of D,L-Lactide and Glycolide Ester end group 3-month degradation time Biodegradable Ideal for terminal sterilization Bioabsorbable excipient Suitable for use with small molecules, peptides, proteins, and other substances Non-GMO No added preservatives Cost effective
Applications
Human generic drug formulations Long-acting injectable formulations Price sensitive applications veterinary medicine
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