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LACTEL® 50:50 DL-PLGE, IV 0.76-0.94
LACTEL® 50:50 DL-PLGE, IV 0.76-0.94 is an ester-terminated lactide-glycolide-containing copolymer (CAS No. 26780-50-7) with an inherent viscosity of 0.76─0.94 dL/g in HFIP and a degradation time of 3 months max.
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- Manufacturer: Evonik Corporation
- Product Line: LACTEL® Polymers
- Product: LACTEL® PLGE Polymers
- Industries: Pharmaceuticals
- Authorized Countries: Canada | United States
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United States
Overview
Evonik's LACTEL® 50:50 DL-PLGE, IV 0.76-0.94 is a versatile pellatized excipient polymer with an ester terminated lactide-glycolide base with a mol ratio of 50:50. Manufactured using a streamlined process to produce a cost-effective PLGA copolymer, Evonik's LACTEL® 50:50 DL-PLGE, IV 0.76-0.94 is non-solvent purified and formulated with no-added preservatives. It is commonly recommended for use in the formulation of long-acting injectable formulations in veterinary medicine and human generic drug formulations, exhibiting excellent compatibility with a range of pharmaceutical substance types, including peptides, proteins, nanoparticles, and microparticles.
Specifications
Physical state: Solid
Form: Granules
Color: White to light tan
Inherent viscosity (IV) dL/g: 0.76─0.94 (in HFIP)
Degradation time: <3 months
Density (g/mL): 1.34
Tensile Strength (psi): 6000─8000
Elongation (%): 3─10
Modulus (psi): 2─4x10⁵
CAS No. 26780-50-7
Primary Chemistry: Poly(DL-lactide-co-glycolide)
Features & Benefits
- 50:50 ratio of D,L-Lactide and Glycolide
- Ester end group
- 3-month degradation time
- Biodegradable
- Ideal for terminal sterilization
- Bioabsorbable excipient
- Suitable for use with small molecules, peptides, proteins, and other substances
- Non-GMO
- No added preservatives
- Cost effective
Applications
Human generic drug formulations Long-acting injectable formulations Price sensitive applications veterinary medicine
Related Applications
Pharmaceuticals
Related Functions
Pharmaceuticals
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