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LACTEL® 50:50 DL-PLGE, IV 0.95-1.20
LACTEL® 50:50 DL-PLGE, IV 0.95-1.20 is a cost-effective PLGA-based copolymer characterized by its high inherent viscosity of 0.95─1.20 dL/g in HFIP and its controlled degradation period of 6 months.This white to tan pellatized solid is designed for pharmaceutical and medical applications, providing controlled drug release.
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- Manufacturer: Evonik Corporation
- Product Line: LACTEL® Polymers
- Product: LACTEL® PLGE Polymers
- Industries: Pharmaceuticals
- Authorized Countries: Canada | United States
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Canada
United States
Overview
LACTEL® 50:50 DL-PLGE, IV 0.95-1.20 is an innovative controlled-release excipient with a polymer composition of 50 mol % D,L-lactide and 50 mol % Glycolide with an ester end group and no added preservatives. As part of Evonik's LACTEL® polymer line, it offers exceptional controlled release of pharmaceutical ingredients in long-acting injectable formulations for veterinary medicine and human generic drug formulations. It is compatible numerous substance types ranging from peptides and proteins to nanoparticles and microparticles. Due to its excellent bioabsorbability it is fully metabolized by the body, offering a degradation period of 6 months with no added preservatives or GMO contents.
Specifications
Physical state: Solid
Form: Granules
Color: White to light tan
Inherent viscosity (IV) dL/g: 0.95─1.20 (in HFIP)
Degradation time: <6 months
Density (g/mL): 1.34
Tensile Strength (psi): 6000─8000
Elongation (%): 3─10
Modulus (psi): 2─4x10⁵
CAS No. 26780-50-7
Primary Chemistry: Poly(DL-lactide-co-glycolide)
Features & Benefits
- 50:50 ratio of D,L-Lactide and Glycolide
- Ester end group
- 6-month degradation time
- Biodegradable
- Ideal for terminal sterilization
- Bioabsorbable excipient
- Suitable for use with small molecules, peptides, proteins, and other substances
- Non-GMO
- No added preservatives
- Cost effective
Applications
Human generic drug formulations Long-acting injectable formulations Price sensitive applications veterinary medicine
Related Applications
Pharmaceuticals
Related Functions
Pharmaceuticals
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