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LACTEL® 65:35 DL-PLGE, IV 0.83-0.93
LACTEL® 65:35 DL-PLGE, IV 0.83-0.93 is a high-quality pharmaceutical polymer designed to provide controlled drug delivery to parenteral drug systems with a 65:35 ratio of D,L-Lactide and glycolide. It exhibits inherent viscosity of 0.83─0.93 dL/g in HFIP and a degradation time of 4 months maximum.
LACTEL® 65:35 IV 0.83-0.93 is an ester-terminated poly(D,L-lactide-co-glycolide) co-polymer designed for use with long-acting injectable formulations in veterinary medicine and human generic drug formulations, exhibiting excellent compatibility with a range of pharmaceutical substance types, including proteins, peptides, microparticles, and nanoparticles. It contains a blend of 65 mol % D,L-lactide and 35 mol % Glycolide with no added preservatives. Due to its excellent bioabsorbability it is fully metabolized by the body, offering a degradation period of 6 months
Specifications
Physical state: Solid Form: Granules or pellets Color: White to yellowish, off-white to light tan Inherent viscosity (IV) dL/g: 0.83─0.93 (in HFIP) Degradation time: <4 months Density (g/mL): 1.30 Tensile Strength (psi): 6000─8000 Elongation (%): 3─10 Modulus (psi): 2─4x10⁵ CAS No. 26780-50-7
Primary Chemistry: Poly(DL-lactide-co-glycolide)
Features & Benefits
65:35 ratio of D,L-Lactide and Glycolide Ester end group 4-month degradation time Biodegradable Ideal for terminal sterilization Bioabsorbable excipient Suitable for use with small molecules, peptides, proteins, and other substances Non-GMO No added preservatives Cost effective
Applications
Human generic drug formulations Long-acting injectable formulations Price sensitive applications veterinary medicine
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