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LACTEL® 65:35 DL-PLGE, IV 0.83-0.93
LACTEL® 65:35 DL-PLGE, IV 0.83-0.93 is a high-quality pharmaceutical polymer designed to provide controlled drug delivery to parenteral drug systems with a 65:35 ratio of D,L-Lactide and glycolide. It exhibits inherent viscosity of 0.83─0.93 dL/g in HFIP and a degradation time of 4 months maximum.
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- Manufacturer: Evonik Corporation
- Product Line: LACTEL® Polymers
- Product: LACTEL® PLGE Polymers
- Industries: Pharmaceuticals
- Authorized Countries: Canada | United States
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Authorized Countries
Canada
United States
Overview
LACTEL® 65:35 IV 0.83-0.93 is an ester-terminated poly(D,L-lactide-co-glycolide) co-polymer designed for use with long-acting injectable formulations in veterinary medicine and human generic drug formulations, exhibiting excellent compatibility with a range of pharmaceutical substance types, including proteins, peptides, microparticles, and nanoparticles. It contains a blend of 65 mol % D,L-lactide and 35 mol % Glycolide with no added preservatives. Due to its excellent bioabsorbability it is fully metabolized by the body, offering a degradation period of 6 months
Specifications
Physical state: Solid
Form: Granules or pellets
Color: White to yellowish, off-white to light tan
Inherent viscosity (IV) dL/g: 0.83─0.93 (in HFIP)
Degradation time: <4 months
Density (g/mL): 1.30
Tensile Strength (psi): 6000─8000
Elongation (%): 3─10
Modulus (psi): 2─4x10⁵
CAS No. 26780-50-7
Primary Chemistry:
Poly(DL-lactide-co-glycolide)
Features & Benefits
- 65:35 ratio of D,L-Lactide and Glycolide
- Ester end group
- 4-month degradation time
- Biodegradable
- Ideal for terminal sterilization
- Bioabsorbable excipient
- Suitable for use with small molecules, peptides, proteins, and other substances
- Non-GMO
- No added preservatives
- Cost effective
Applications
Human generic drug formulations Long-acting injectable formulations Price sensitive applications veterinary medicine
Related Applications
Pharmaceuticals
Related Functions
Pharmaceuticals
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