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- Manufacturer: Evonik Corporation
- Product Line: LACTEL® Polymers
- Product: LACTEL® PLGE Polymers
- Industries: Pharmaceuticals
- Authorized Countries: Canada | United States
LACTEL® 75:25 DL-PLGE, IV 0.80-1.20
LACTEL® 75:25 DL-PLGE, IV 0.80-1.20 is an innovative controlled-release excipient with an ester-terminated lactide-glycolide base with a mol ratio of 75:25. With an inherent viscosity of 0.80─1.20 dL/g in HFIP and a degredation period of 6 months, LACTEL® 75:25 DL-PLGE offers excellent stability and performance in controlled drug release applications.
Quantity
Documents
Specifications
Physical state: Solid
Form: Granules or pellets
Color: White to yellowish, off-white to light tan
Inherent viscosity (IV) dL/g: 0.80─1.20 (in chloroform)
Degradation time: <6 months
Density (g/mL): 1.30
Tensile Strength (psi): 6000─8000
Elongation (%): 3─10
Modulus (psi): 2─4x10⁵
CAS No. 26780-50-7
Primary Chemistry:
Poly(DL-lactide-co-glycolide)
- Manufacturer: Evonik Corporation
- Product Line: LACTEL® Polymers
- Product: LACTEL® PLGE Polymers
- Industries: Pharmaceuticals
- Authorized Countries: Canada | United States
Manufacturer
Product Line
Product
Industries
Authorized Countries
Canada
United States
Overview
LACTEL® 75:25 DL-PLGE, IV 0.80-1.20 is a functional excipient from Evonik containing a 75:25 mol ratio of D,L-Lactide and Glycolide with a uniform degredation period of 6 months for controlled drug delivery. It is compatible with numerous substance types ranging from peptides and proteins to nanoparticles and microparticles in the formulation of long-acting injectable formulations in veterinary medicine and human generic drug formulations.
Specifications
Physical state: Solid
Form: Granules or pellets
Color: White to yellowish, off-white to light tan
Inherent viscosity (IV) dL/g: 0.80─1.20 (in chloroform)
Degradation time: <6 months
Density (g/mL): 1.30
Tensile Strength (psi): 6000─8000
Elongation (%): 3─10
Modulus (psi): 2─4x10⁵
CAS No. 26780-50-7
Primary Chemistry:
Poly(DL-lactide-co-glycolide)
Features & Benefits
- 75:25 ratio of D,L-Lactide and Glycolide
- Ester end group
- 6-month degradation time
- Biodegradable
- Ideal for terminal sterilization
- Bioabsorbable excipient
- Suitable for use with small molecules, peptides, proteins, and other substances
- Non-GMO
- No added preservatives
- Cost effective
Applications
Human generic drug formulations
Long-acting injectable formulations
Price sensitive applications
veterinary medicine
Related Applications
Pharmaceuticals
Related Functions
Pharmaceuticals
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