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Methyl Magnesium Chloride
Methyl magnesium chloride (MeMgCl) is an organomagnesium compound widely used as a fundamental component for synthesis in a broad spectrum of applications.
Methyl magnesium chloride, also referred to as a Grignard reagent, plays a vital role in nucleophilic substitutions and acts as a potent base, particularly when combined with an amine. Methyl magnesium chloride exhibits a decreased reactivity compared to bromide, enabling the use of gentler reaction conditions, particularly in the presence of competing bases.
Specifications
Form: Liquid Color: Translucent CAS number: 676-58-4 EINECS number: 211-629-7 Formula: CH3ClMg Titer (moles/kg solution): 3.0 Molecular weight: 74.8 Weight percent active: 21–22 Reactivity: Water/oxygen reactive Specific gravity at 25°C: 1.01 Flash point (THF) (tag closed cup): −17°C (1.4°F) Autoignition temperature (THF): 321°C (610°F) Solvent: Tetrahydrofuran (THF)
Primary Chemistry: Methyl magnesium chloride
Features & Benefits
Strong nucleophile Reactivity enables a wide range of chemical transformations Versatile carbon–carbon bond formation High reactivity and selectivity Compatible with various solvents
Problems Solved
Synthesis of alcohols Lack of compatibility with solvents
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